http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017211775-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_095fc4a13daf2773d72648d379b28b7d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01085 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-306 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-32 |
| filingDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c83d39879aa9a244aaa4508635282a82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f4d5595a8264f09781c46b8701ac4b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f06466c745b1b6362eacb7d21a8a123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb30b4bbc4ac6659b69d062a7703a953 |
| publicationDate | 2017-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2017211775-A1 |
| titleOfInvention | Method for the purification of biological macromolecular complexes |
| abstract | The present invention relates in a first aspect to a method for the purification of biological macromolecular complexes. Typically, no chromatography steps are applied. That is, the present invention relates to a method for the purification of biological macromolecular complexes Furthermore, the present invention relates to a method for crystallization of biological macromolecular complexes comprising the step of purification as described followed by crystallization in a reservoir solution containing a water-soluble polymer. Furthermore, purified biological macromolecular complexes obtainable by the method according to the present invention are provided as well as crystallized biological macromolecular complexes. Finally, a method for determining the suitability of a candidate compound for inhibiting the 20S proteasome of an individual is provided. Said method is particularly useful in personalized medicine identifying suitable inhibitors of the 20S proteasome in individuals for treating, ameliorating or preventing a cancer, an autoimmune disease, a muscular dystrophy, emphysema or cachexia accompanying cancer or AIDS. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3712263-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020188074-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113853431-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020188074-A3 |
| priorityDate | 2016-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 225.