| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46cb3dfdd38a34ce27bf0e2323d90a6a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-905 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
| filingDate |
2017-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e028bd7596f6129b1de9541a7208c322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c18c41c5ef03b750cbabbac4c83741af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_550fe00cc0c0d6020a14e0afca9cf661 |
| publicationDate |
2017-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017201311-A2 |
| titleOfInvention |
Compositions and methods for genomic integration of nucleic acids into exogenous landing pads |
| abstract |
Provided herein are compositions and methods of integrating one or more exogenous donor nucleic acids into one or more exogenous landing pads engineered into a host cell's genome. In certain embodiments, the exogenous landing pads and exogenous donor nucleic acids comprise standardized, compatible homology regions so that exogenous donor nucleic acids can integrate into any of the landing pads, independent of the genomic sequences surrounding the landing pads. In certain embodiments, the methods comprise contacting the host cell comprising landing pads with one or more exogenous donor nucleic acids, and a nuclease capable of causing a double-strand break within the landing pads, and recovering a host cell comprising one or more exogenous donor nucleic acids integrated in any of the landing pads. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11236313-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667911-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021253372-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022061417-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023025834-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11680268-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597924-B2 |
| priorityDate |
2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |