http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017198617-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67aa9f927ee002165dc02fdfa78098a1 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2017-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e270e8e3cd7bbc2328565d563ea64c88 |
publicationDate | 2017-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2017198617-A1 |
titleOfInvention | Method for assessing a prognosis and predicting the response of patients with malignant diseases to immunotherapy |
abstract | The invention relates to, among others, a method for assessing a prognosis of a patient with a malignant disease and/or for predicting the response of a patient with a malignant disease to immunotherapy. For this purpose, a DNA methylation analysis is carried out on at least one immunoregulatory gene of cells of the malignant disease and/or T lymphocytes which interact with the cells of the malignant disease, said gene coding for an immune checkpoint selected from B7 proteins and the receptors thereof, MHC-peptide complex-binding co-receptors, the members of the tumor necrosis factor receptor superfamily TNFRSF9, CD40, TNFRSF4, TNFRSF18, and CD27, the members of the immunoglobulin superfamily TIGIT, BTLA, HAVCR2, BTNL2, and CD48, and the andenosine-binding adenosine 2A receptor. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3885454-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021190983-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597975-B2 |
priorityDate | 2016-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 798.