http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017194735-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f422ac028a4af49898a3d32e38e2008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0cbaaf7094d0b513aff52bba5bcd08b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_850c9064e908d16877419265b5ed5a04 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e59cda8dfb8c5dba1d4bffc014fb2e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2078752ab14b4959e29e807c29915afc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a460862981b5acdbe4510cbb510e6a75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af02bc8059a3f2fd430d42f94de3a435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4892bfc27401ecb98bb0db822f71e606 |
| publicationDate | 2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2017194735-A1 |
| titleOfInvention | Methods and kits for predicting or assessing the severity of infections caused by staphylococcus aureus |
| abstract | The invention relates to methods and kits for predicting or assessing the severity of infections caused by Staphylococcus aureus . Staphylococcus aureus is a commensal and a pathogen, and uncovering the identifying markers of the 'colonization to disease' transition is very useful. Several S. aureus small RNAs regulate virulence. The presence/absence and expression of eight sRNAs were investigated in 83 strains from 42 sepsis or shock patients, and 41 carriers. These isolates were characterized by MLST and spa typing and monitored for virulence and resistance. RNAIII expression was lower in strains from shock patients than from colonizing strains. Noteworthy, when RNAIII was associated with SprD, colonizing strains were significantly discriminated from those from patients with bloodstream infections, including sepsis and shock. Isolates associated with colonization may have different sRNA and sRNA target expressions than disease isolates. Monitoring RNAIII and SprD expressions could inform about infection severity. Thus, the invention relates to a method of assessing of predicting or assessing severity of an infection caused by Staphylococcus aureus comprising quantifying the RNAIII and/or SprD expression level in bacteria recovered from a culture obtained from the patient. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11495359-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108588198-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108642192-A |
| priorityDate | 2016-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 410.