| abstract |
The present invention provides a means with which it is possible to efficiently produce a fused substance of an Fc protein and a target substance (for example, a peptide). Specifically, the present invention provides an azide group-containing Fc protein or the like represented by formula (1): N 3 -L a -Phe-L b -Fc (1) [in the formula, N 3 represents an azide group, L a represents a bond or a divalent group, Phe represents a residue of phenylalanine or a derivative thereof, L b represents a lysine residue or arginine residue, or a peptide linker comprising two or more amino acid residues having a lysine residue or arginine residue at the N terminal, and Fc represents an Fc protein.]. |