http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017186853-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e381573e6389d6a4cb9715a649009cf4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa02f0b13914e0376ea9b3e22c50fad0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 |
| filingDate | 2017-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90e6bdf6de582cb8d1e28d80b3eaaa6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5f524dbfe8660393d9a780771ae512d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efc93fb5de92b38fd2ae0af7d966f737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78032fce2366d6df921b775303dceee7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0972b0b46eb2a42c0263e8d016e98503 |
| publicationDate | 2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2017186853-A1 |
| titleOfInvention | T cell-based bi-specific immunotherapeutics |
| abstract | The present invention provides compositions and methods for immunotherapy in humans. The invention includes a bi-specific B cell receptor like complex expressed in T cells and comprising a bi-specific extracellular antigen recognition domain, a trans-membrane domain, a CD79αβ heterodimer, and a signaling region that controls T cell activation. The bi-specific extracellular antigen recognition domain and trans-membrane domain are from the same bi-specific human or humanized Ig-like molecule in the complex. The signaling region comprises a T cell signaling domain in combination with a co-stimulatory signaling domain. The signaling domain is fused to the CD79αβ heterodimer. |
| priorityDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 324.