| abstract |
Disclosed are compounds of Formula (I), or a salt thereof, wherein: X is CR 4 or N; Y is CR 4 or N, provided that Y is N only if X is N; R 1 is Formulae (A) or (B); each W is independently NR 1b or O; Z is a bond or CHR 1d ; and R 1 , R 2 , R 3 , R 4 , L 1 , R 1a , R 1b , R 1c , and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases. |