http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017183215-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf2b5f31694e5a8ff70291ee34e8f937 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-12 |
| filingDate | 2016-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c824d262c0327f7bf8e52881f5f161fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc4fa80ebeaf5b6246bdb365f3a8c6ce |
| publicationDate | 2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2017183215-A1 |
| titleOfInvention | Sugar moiety silyl ether derivative of 5-azacytidine |
| abstract | [Problem] To provide, as a substitute for a clinically used injected drug (5-azacytidine or 2'-deoxy-5-azacytidine), a 5-azacytidine or 2'-deoxy-5-azacytidine prodrug having high stability against the metabolic enzyme cytidine deaminase, as a therapeutic drug for various bone marrow tumors including myelodysplastic syndrome. [Solution] The aforementioned problem is solved by a compound, or salt thereof, represented in formula (1) (In the formula, R is an OR3 group or a hydrogen atom, R1, R2 and R3 are each a hydrogen atom or a silyl group represented by formula (2) (in that formula, R4, R5 and R6 are each an alkyl group optionally having a substituent, an aryl optionally having a substituent, or an arylalkyl group optionally having a substituent.) However, R1, R2 and R3 cannot all simultaneously be a hydrogen atom.). |
| priorityDate | 2016-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 277.