http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017181831-A1

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filingDate 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dbdafaa5ae4a8b39276a912e5232d04
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publicationDate 2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2017181831-A1
titleOfInvention Anti-microbial composition for treating gram-negative bacterial infection
abstract The present invention discloses an anti-microbial composition for treating Gram-negative bacterial infection. The composition comprises: TNP-2092 and a cell membrane penetrating agent. The cell membrane penetrating agent is polymyxin B or polymyxin E. The anti-microbial pharmaceutical composition for treating Gram-negative bacterial infection uses a joint application of TNP-2092 and the cell membrane penetrating agent to treat Gram-negative bacterial infection. The invention provides better anti-microbial activity when compared to using only TNP-2092 or the cell membrane penetrating agent. The invention achieves synergy in anti-microbial activity, and can be used to treat Gram-negative bacterial infections, including an infection of a drug resistant bacteria.
priorityDate 2016-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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