| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7aab41d5b2f11e22377b7628d3e9f5d3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-498
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-498
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-36 |
| filingDate |
2017-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc443ae8ab1c6977823f8bebfa587c5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57d4f071e6bfe67cdd5d46ae96ffec82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a890650ef88c0a9086fd2750238b98b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31a998b1c48728b4dc575c27884941d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d3e4c0299a2328969335123d31717d6 |
| publicationDate |
2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017176040-A1 |
| titleOfInvention |
Heterocyclic compound decomposing ras and uses thereof |
| abstract |
The present invention relates to a compound which simultaneously degrades β-catenin and a Ras protein comprising a K-Ras mutation. The compound according to the present invention induces the inhibition of cancer proliferation and the death of cancer cells by regulating a signal input into a key signal transduction system involved with cancer, thereby exhibiting an effect on the treatment of cancer in cancer patients showing resistance to conventional anticancer agents due to Wnt signal transduction abnormality and Ras gene mutation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023121184-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11649231-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019235879-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190139637-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112368279-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102297501-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019209083-A1 |
| priorityDate |
2016-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |