| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70571
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y401-01015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0075 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-69 |
| filingDate |
2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37f6085184e30103c69014aef86e7b81 |
| publicationDate |
2017-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017172606-A1 |
| titleOfInvention |
Method and composition for treating neuronal hyper-excitability |
| abstract |
The present invention provides a therapy for treating loss of GABA-mediated pre-synaptic inhibition after spinal injury. The therapeutic regimen includes spinal segment-specific upregulation of GAD65 (glutamate decarboxylase) and VGAT (vesicular GABA transporter) to modulate chronic spasticity in patients after spinal traumatic or ischemic injury. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3678709-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11707535-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10980566-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-D963164-S
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019243574-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111093716-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11472859-B2 |
| priorityDate |
2016-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |