http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017155325-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69f43505d1b3ec31c224b32b5d1ec4e2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-40 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
| filingDate | 2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bf722c9b9b25555a1e6d30ee34cefcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_890748d733dc221082a0b81efde2a183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b172b8a3ca1493fdbd68fb8291aa1f40 |
| publicationDate | 2017-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2017155325-A1 |
| titleOfInvention | Composition for proliferation, differentiation promotion, or senescence inhibition of stem cells, containing jak1 inhibitor as active ingredient |
| abstract | The present invention relates to a composition for proliferation, differentiation promotion, and senescence inhibition of stem cells, containing a JAK1 inhibitor as an active ingredient. JAK1 inhibitor-treated stem cells or JAK1 knockout stem cells, of the present invention, have an activity for decreasing senescence and increasing the survival rate of the stem cells, thereby being usable in a composition for proliferation, differentiation promotion, and senescence inhibition of stem cells. In addition, JAK1 knockout stem cells have an activity for inhibiting or decreasing the expression of HLA-A or HLA-B, which is an immunogenicity related protein, and promoting or increasing the expression of TGF-b or HGF, which is a T cell activity inhibitory protein, thereby also being usable in the prevention or treatment of immune diseases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112626009-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112626009-B |
| priorityDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.