Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e5fbdb2b31c9d7af515b9aa72d68221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be2c55a9de09e08e3404c0a5a1ae4dc7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-84 |
filingDate |
2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46c2b8eebcdf7e7d461b8e4fe06ae21d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_054a7be4cb0df32b791bf755ecb86ad7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dfdd0c21d87b0a73944caaef40c9fab |
publicationDate |
2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2017153570-A3 |
titleOfInvention |
PH-SENSITIVE NUCLEIC POLY COMPLEXES |
abstract |
The present invention relates to the field of small pH sensitive tools, in particular for measuring a pH value in biological media. I-patterned DNA structures have been widely used in the state of the art for the manufacture of nanodevices; however, assistance in folding a multi-stranded I-pattern, particularly at physiological pH, remains a challenge. The inventors have devised a pH-sensitive tool based on a multi-stranded I-pattern that comprises a complex of poly (nucleic acids) instead of the mono (nucleic acid) complexes that were known in the state of the art. The poly (nucleic acid) complex according to the invention is much easier to design and can be easily adapted according to the pH range of interest to be measured. The polynucleic complexes of the invention are useful for the design of various pH-sensitive devices and in particular pH biosensors and pH-sensitive delivery systems, particularly in the pharmaceutical field. |
priorityDate |
2016-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |