http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017147958-A1

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filingDate 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9cb60df2bf9930baa728017f3364a01
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publicationDate 2017-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2017147958-A1
titleOfInvention Use of oxygen-containing hydrocarbon derivative as polymyxin synergist
abstract Disclosed are a pharmaceutical composition comprising a polymyxin synergist and the use thereof. The oxygen-containing hydrocarbon derivative containing 4 to 18 carbon atoms includes a fatty alcohol, a fatty acid and a fatty acid glyceride and serves as a polymyxin synergist, in particular as a synergist for a strain sensitive to the polymyxin inhibiting effect and as a drug-resistance reversal agent for polymyxin. Also disclosed is a pharmaceutical composition of the polymyxin synergist. The pharmaceutical composition is further used for preparing a drug and an animal feed additive for the treatment of a disease caused by polymyxin-sensitive bacterial infection or drug-resistant bacterial infection, and provides a more effective application space for the use of polymyxin, and is of great importance in application in the fields of pharmaceutics and animal breeding.
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priorityDate 2016-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 31.