| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2aa388e460f6cf478bd46c925c6ab10e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 |
| filingDate |
2017-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40d864607cc3a20c353d8d9b07765986
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c21245c9b7ad5e0e697c4fb12257e61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f387c79a0591081cc4e597fb59abddcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7378835ef5b934cc70b2a8c29948054e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_651cf4406c8ee5eeef3e4d18394e1187 |
| publicationDate |
2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017141271-A1 |
| titleOfInvention |
Stable pharmaceutical composition of afatinib |
| abstract |
A solid oral dosage form comprising therapeutically effective amount of afatinib or a salt thereof and an acid in an amount sufficient to provide an acidic microenvironment of pH less than 3.5, wherein the solid dosage form is a dry solid dosage form and wherein when the solid oral dosage form is stored at condition of 40°C and 75% relative humidity for three months, the total impurities in the solid oral dosage form do not increase to more than 2.5% by weight of afatinib. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110833534-A |
| priorityDate |
2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |