| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22b9baa71ceef111b94d9fcf4391f1f0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J39-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J41-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01F15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J49-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-1871
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G21G1-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-362 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G21G1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J41-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J39-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-06 |
| filingDate |
2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_125f4ee726e5671711787c96159bdbf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42d667791b20752e2c78bdc2ca0108c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3131fc3d5b6c4cacd3a4d2a9f90a9cce |
| publicationDate |
2017-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017118591-A1 |
| titleOfInvention |
Isotope preparation method |
| abstract |
The present invention comprises a method for the generation of 227 Th of pharmaceutically tolerable purity comprising i) preparing a generator mixture comprising 227 Ac, 227 Th and 223 Ra; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting a mixture of said 223 Ra and 227 Ac from said strong base anion exchange resin using a first mineral acid in an aqueous solution; iv) eluting 227 Th from said strong base anion exchange resin using a second mineral acid in an aqueous solution whereby to generate a first 227 Th solution containing contaminant 223 Ra and 227 Ac; v) loading the first 227 Th solution onto a strong acid cation exchange resin; vi) eluting at least a part of the contaminant 223 Ra and 227 Ac from said strong acid cation exchange resin using a third mineral acid in aqueous solution; and vii) eluting the 227 Th from said strong acid cation exchange resin using a first aqueous buffer solution to provide a second 227 Th solution. Purified thorium-227 of pharmaceutical purity and a pharmaceutical composition comprising the same are also provided. |
| priorityDate |
2016-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |