http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017108724-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30a7bcefaec4efdf749c936726d5d64a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a61c11d10dd703b85946a6f210e064f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d47ea4a98d4d599e0ff810991424307 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-874 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D3-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-84 |
| filingDate | 2016-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0dfc41fd2eae2669f23c74e46914d15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7660cf4fd6c80bae7703b576e5032e8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da253505ec203c7f7cb65487ab082298 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3105a02f9d6d1c24f3881ed1f610225c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0730d3f883f9d1c88215ce26e7685a3 |
| publicationDate | 2017-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2017108724-A1 |
| titleOfInvention | Method of delivering an active agent to skin |
| abstract | A method of delivering an active agent to skin, preferably axilla, comprising the steps of: a) applying to skin a composition comprising at least 0.1 wt% of core shell microcapsules whereby the microcapsules come into contact with the skin each microcapsule having an inner shell formed of a first synthetic polymer and containing the active agent and the inner shell capable of allowing at least a portion of the active agent to pass from inside the inner shell to outside the inner shell to enable it to come into contact with the skin, the inner shell being coated with a coating of insoluble polyamide with a solubility in water of less than 1g/L at 25°C, the polyamide formed by the reaction of: (iii) at least one low molecular weight dicarboxylic acid having from 3 to 12 carbon atoms, or ester thereof; (ii) at least one poly(alkylene glycol) polyamine having the formula (I) H 2 N-(-C(R)H-CH 2 -O-)x-C(R)H-CH 2 -NH 2 (I) where x ranges from about 2 to 5, R is an alkyl of one to four carbon atoms; (iii) optionally, at least one high molecular weight dicarboxylic acid (dimer) having from 20 to 40 carbon atoms, or ester thereof; and wherein the coating further comprises a crosslinker to improve hardness and further reduce solubility, such that, while the coating is present the release of the active agent onto the skin is retarded; b) Sweating to produce sweat that comes into contact with at least part of the polyamide coating; c) Degrading the polyamide coating by the action of protease enzymes present in the sweat thereby to cause delayed release of the active agent onto the skin, preferably over a period of from 1 hour to 2 days after the microcapsule first comes into contact with sweat. |
| priorityDate | 2015-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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