| abstract |
A method for producing derivatives of N- retinoylaminoalkane sulfonic acid, the method comprising providing retinoic acid, chloroformate, aminoalkanesulfonic acid selected from the group consisting of cysteic acidand alkyl ester thereof, cysteinesulfinic acid and alkyl ester thereof, homocysteic acid and alkyl ester thereof, homocysteinesulfinic acid and alkyl esters thereof, taurine and derivatives thereof, and an organic solvent,and a base, mixing said components under substantial absence of oxidizing compoundsthereby forming a reaction mixture comprising a liquid phase, wherein the liquid phase is one phaseand the derivatives of N-retinoylaminoalkane sulfonic acid are formed in said liquid phase. |