| abstract |
The present invention relates to pyrazolopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-1H-pyrazolo[3,4-c]pyridazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, wherein X, R 1 , R 2 , R 3 , R 4 and R 5 are as defined in the description. The pyrazolopyridazine derivatives of the present invention modulate the activity of the GABA A receptor. They may useful in the treatment of a number of conditions, including pain and epilepsy. |