| abstract |
The present invention relates to amino acid sequences and polypeptides binding to the P2X7 receptor. In particular, the present invention relates to improved heavy-chain immunoglobulin single variable domains (also referred to herein as "ISV's" or "ISVD's" ) binding to the P2X7 receptor, as well as to proteins, polypeptides and other constructs, compounds, molecules or5 chemical entities that comprise such ISVD's. |