| abstract |
A topical formulation comprising a first active agent that is pharmaceutically acceptable salt of a cationic bisbiguanide such as chlorhexidine digluconate (CHG), a secnd active agent which is a cationic quaternary ammonium compound such as cetylpyridinium chloride (CPC), methylisothiazolone, or chloroxylenol, and a propellant; and an aerosol dispenser containing the topical formulation. The topical formulation can be sprayed onto exposed skin to prevent or reduce the risk of skin infection. |