Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee37266afad7a55d90aef0ddc053cf57 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5415 |
filingDate |
2016-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597a83116bf2582db4cb93d458c2a4e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e24764c4216c803e4b1fa840f6ca1e0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc76f0738afb913e2f833ccca7663e1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6211de9f46b2761af595e3e487e33272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cb9c5c9b1e7d9dc0e7d18e37862a6de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca3f83f56c845d672fac5c1fd7e1287f |
publicationDate |
2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2017051046-A1 |
titleOfInvention |
Aminophenothiazines for modulating the number of synapses |
abstract |
The invention relates to the use of a group of compounds with a phenothiazine nucleus of general formula (I) for the treatment of diseases of the central nervous system which present synapse abnormalities, such as autism or fragile X syndrome. The compounds according to the invention intervene in the interaction of the NCS1 and Ric8 proteins involved in the process of synaptogenesis. |
priorityDate |
2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |