http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017045456-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78ffff675e713da9a407870d408da3df |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-097 |
filingDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9663dde47766f2141d58aeaefc73c6e6 |
publicationDate | 2017-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2017045456-A1 |
titleOfInvention | Cyclic peptide compound and use thereof |
abstract | Disclosed is a cyclic peptide compound of a chemical structure as shown by general formula I, or a pharmaceutically acceptable salt, isomer, racemate, prodrug or solvate thereof. Compared with the positive control (SAHA), the compound has a significant activity in terms of inhibiting the deacetylation of HDAC enzymes (mainly HDAC1, HDAC2, HDAC3, HDAC8 and HDAC11), which are closely related to tumour proliferation and metastasis; and it also has a significant activity in terms of inhibiting the growth of tumour cells. |
priorityDate | 2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.