http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017045456-A1

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-097
filingDate 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9663dde47766f2141d58aeaefc73c6e6
publicationDate 2017-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2017045456-A1
titleOfInvention Cyclic peptide compound and use thereof
abstract Disclosed is a cyclic peptide compound of a chemical structure as shown by general formula I, or a pharmaceutically acceptable salt, isomer, racemate, prodrug or solvate thereof. Compared with the positive control (SAHA), the compound has a significant activity in terms of inhibiting the deacetylation of HDAC enzymes (mainly HDAC1, HDAC2, HDAC3, HDAC8 and HDAC11), which are closely related to tumour proliferation and metastasis; and it also has a significant activity in terms of inhibiting the growth of tumour cells.
priorityDate 2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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