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filingDate 2016-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2017044573-A1
titleOfInvention Multi-layered biomimetic material and method of formation
abstract Biocompatible biomimetic materials that exhibit desirable mechanical properties while also encouraging cell ingrowth and proliferation are described. The biomaterials include a multi-layer laminate of three or more decellularized aligned collagen tissues. The individual layers are aligned with one another in an angle-ply arrangement, with the collagen of each layer aligned at an angle to the collagen of the adjacent layer. The biomaterials are useful as collagenous graft materials such as a patch for a hernia in an annulus fibrosus or grafting materials for repair of tendons, ligaments, cartilage and other musculoskeletal tissues.
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