abstract |
Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, antiinflammatory, anti-microbial, and/or cell-adhesion specificity to a surface or material in need thereof, such as a surface of an indwelling medical implant, or a marine surface. The porphyrine compounds are characterized by having the following group attached to the porphyrine core through a carboxylate ester group: A is independently an optionally substituted N-heterocyclic aromatic ring; x is independently an integer from 0 to 6; R 2 is independently lower aminoalkyl or lower aminoaryl. An example of the claimed compounds is the following: |