http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017030900-A1

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publicationDate 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2017030900-A1
titleOfInvention Quantitative tool using impedance spectroscopy to monitor fracture healing
abstract A system for monitoring or observing a property or condition of a bone includes a first electrode and a second electrode configured to be implanted into the bone so as to be in electrical connection with each other through at least a portion of the bone or the bone fracture region, and a variable frequency power supply electrically connected to the first and second electrodes to provide a source signal. The system includes a detection system electrically connected between the first and second electrodes and configured to detect phase-sensitive current and voltage of a circuit formed by the variable frequency power supply, the first and second electrodes and the bone, and to provide detection signals for each of a plurality of frequencies. The system also includes a signal processor arranged to communicate with the detection system to receive the detection signals, the signal processor being configured to process the detection signals to calculate a complex impedance of the bone substrate corresponding to each of the plurality of frequencies to provide an output impedance spectrum.
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