| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ba1ce9553533b09bf3c041599a72f42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01633eafe000febcc9a3b7d470d1de75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3852eb9b97101031c506ee9dfa760f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a5c7953b6d11042bb17445b3ee0f3c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af1664ac24971d095258ba5ed7da1f51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3c2e77f8dfda692ca527454d23ecc03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e5ba82cb828838f325f3e8e7d6728b0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2313
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0648
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0634
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0642 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate |
2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96a6022dd793316a5e77df5ebbf7cc6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53cbfd44e984e1aaf7727e705e7bd198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8b06377143d6b6925026270c90db8f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_230d97ca8ed14eda68894e48d6f1340e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9861d942235edbab85e5a917decbb4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7547613639b6d02018b0a22b92e3779c |
| publicationDate |
2017-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017024213-A1 |
| titleOfInvention |
Modulating inflammasome activation of myeloid-derived supperssor cells for treating gvhd or tumor |
| abstract |
In one aspect, a method of treating a subject having or at risk of having graft-versus-host disease (GvHD) generally includes administering to the subject a plurality of myeloid-derived suppressor cells (MDSCs) effective to ameliorate at least one symptom or clinical sign of graft- versus-host disease compared to a suitable control subject. In another aspect, a method of treating a tumor in a subject generally includes administering to the subject an anti-tumor therapy and co-administering to the subject an inflammasome inciting agent in an amount effective to increase inflammasome activation of MDSCs sufficiently to reduce suppressor function of the MDSCs. |
| priorityDate |
2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |