| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_863dddc7125f4b0d446c3223ebaadfab |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-569 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 |
| filingDate |
2016-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f898032c206cc6451404ad438f1f2c5a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01ea0b8d720d54e8638cd352da366c90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae09bcd072591b49d81affc19b0da0ed |
| publicationDate |
2016-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016201127-A1 |
| titleOfInvention |
Methods of optimizing nucleotide sequences encoding engineered influenza proteins |
| abstract |
The disclosure provides methods for generating an optimized nucleotide sequence encoding an engineered influenza structural protein and the optimized nucleotide sequences obtained therefrom. The optimized nucleotide sequences can be used in a reverse genetics system to facilitate the rescue of infectious influenza virus containing the engineered structural proteins and/or enhance viral titers. Also provided are methods of preparing an influenza vaccine composition using the optimized nucleotide sequences, as well as methods of inducing an immune response using the influenza vaccine composition. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3233116-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11325947-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017210599-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10220086-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844097-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10925957-B2 |
| priorityDate |
2015-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |