| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c87b1f7158bec499783fa1b27aad08c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-01 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0679
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0672
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-407 |
| filingDate |
2016-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bed577a3806e917a0aae12e97a98871
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_499b60914c675575c6597badc0ef04d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5decdf1c9ac7e83e751e4ad446cd88e0 |
| publicationDate |
2016-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016200340-A1 |
| titleOfInvention |
Derivation of hepatic stem cells and mature liver cell types and uses thereof |
| abstract |
This application describes liver stem cells (LSC), and differentiated hepatocytes, cholangiocytes, and 3D cellular structures derived therefrom. Methods for producing LSC and mature, differentiated hepatocytes and cholangiocytes in culture are provided. Also provided are cell culture systems and cell culture media for producing a homogenous population of liver stem cells that remain in an undifferentiated state over multiple passages in culture. The LSC and methods are useful for producing homogenous populations of hepatocytes and cholangiocytes for downstream applications. The LSC can be transplanted into subjects to treat liver diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10683483-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023158836-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021055565-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019216831-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102017110-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022517300-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021069553-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107982518-A |
| priorityDate |
2015-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |