http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016195157-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c063a23c7d2566b228090ee45691626 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 |
| filingDate | 2015-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ab67a12e840b7cef53c971e3190c052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2674b422592823bc63088279a54787f7 |
| publicationDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016195157-A1 |
| titleOfInvention | Human fibroblast growth factor-2 mutant with increased stability, and use thereof |
| abstract | The present invention relates to a highly stable basic fibroblast growth factor mutant, and a use thereof. More specifically, the present invention provides: a highly stable basic fibroblast growth factor (bFGF) mutant, in which two or more amino acids in an amino acid sequence of SEQ ID NO: 1 are substituted with serine and one or more amino acids are substituted with cysteine; a DNA base sequence encoding the bFGF mutant; an expression vector comprising the DNA base sequence; a transformant transformed by the expression vector; a method of producing the bFGF mutant; and a composition comprising the bFGF mutant as an active ingredient. According to the present invention, the bFGF mutant of the present invention has excellent stability in an aqueous solution state and excellent thermal stability, and thus it is possible to produce functional cosmetics and skin inflammation medicines which do not lose activity, unlike conventional wild-type bFGF products, even during distribution and storage. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11207257-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114805534-A |
| priorityDate | 2015-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.