http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016182161-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb6372dde89a8ac6af866c273e9f3f8f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-73 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 |
| filingDate | 2015-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57a97fff07ea3ed713f03a8a60aad3d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d7606fe4c15bf6b45696273e9eb48d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ebd5894a39335e6ac58fc31d2f28ea0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e650450d81488e9d682b8fed2bd81b6 |
| publicationDate | 2016-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016182161-A1 |
| titleOfInvention | Composition containing rubus coreanus extract or fraction thereof as active ingredient for increasing low-density lipoprotein receptor by inhibiting pcsk9 gene expression, and use thereof |
| abstract | The present invention relates to a composition containing Rubus coreanus extract or a fraction thereof as an active ingredient for decreasing the PCSK9 gene expression increased by a statin-based compound or for increasing a low-density lipoprotein receptor (LDLR) decreased by the statin-based compound. The composition of the present invention can lower blood cholesterol level by improving the expression of a low-density lipoprotein receptor by means of inhibition of PCSK9 gene expression. In addition, by lowering the amount of cholesterol in blood, the composition can be utilized in prevention, alleviation or treatment of metabolic diseases such as obesity, diabetes mellitus type 2, hypertension, cardiovascular diseases and hyperlipidemia. |
| priorityDate | 2015-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.