http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016177899-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e7ca4b58ab344b1e155f64e3aaae18e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0634 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate | 2016-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81b731c1cfdd72c8d670d1f52dd66615 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11893ff1d802900f0793aae119a71e02 |
| publicationDate | 2016-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016177899-A1 |
| titleOfInvention | Anti-bacterial agents and their use in therapy |
| abstract | The present invention provides an agent, or a composition containing an agent, for use in treating or preventing a bacterial infection in a subject, wherein said agent comprises: (i) an oligopeptidic compound comprising a PCNA interacting motif and a domain that facilitates the cellular uptake of said compound, wherein the PCNA interacting motif is X 1 X 2 X 3 X 4 X 5 X 6 (SEQ ID NO: 1 ) and wherein: X 1 is a basic amino acid; X 2 is an aromatic amino acid; X 3 is an aromatic amino acid or a hydrophobic amino acid that has an R group comprising at least three carbon atoms; X 4 is an uncharged amino acid other than an aromatic amino acid, Glycine (G) and Proline (P); X 5 is any amino acid other than an acidic amino acid or an aromatic amino acid; and X 6 is any amino acid other than an acidic amino acid or an aromatic amino acid, preferably a basic amino acid or Proline (P), wherein when X 3 is not an aromatic amino acid, X 5 is not lysine (K) and X 6 is a basic amino acid or Proline (P); or (ii) a nucleic acid molecule comprising a sequence encoding the oligopeptidic compound of (i). In certain aspects the agent and composition of the invention may be used as single agents. In other aspects of the invention the agents and composition may be used in conjunction with one or more additional active agents, such as antibiotics, or in combination with UV radiation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022013451-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021078978-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021224068-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3755360-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111867615-A |
| priorityDate | 2015-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1340.