abstract |
Provided is a T cell receptor (TCR) capable of binding specifically antigen short-chain polypeptide SLLMWITQC derived from NY-ESO-1. The antigen short-chain polypeptide is capable of forming a complex with HLA A0201 and being presented together on the surface of a cell. Also provided are a nucleic acid molecule encoding the TCR and a vector comprising the nucleic acid molecule. In addition, the present invention also provides a cell for transducing the TCR of the present invention. |