| abstract |
The present invention relates to novel bacteriocins with a wide antimicrobial activity against bacteria, including food spoilage and pathogenic bacteria, and the genes that encode said bacteriocins. In particular, the present invention relates to the isolation, characterization and use of a novel cyclic bacteriocin, Plantacyclin B21AG and biologically active fragments and variants thereof, and the genes associated with Plantacyclin B21AG production and its cyclization and their application as a potential heterologous expression system for the expression of cyclised proteins, and transfer of these genes to other related bacterial strains. |