| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_280d87031f0c5786de1808713a1b76b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f16452705a599d4374a4aecbc73ec9ad |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0c62110c15c800fc3a6654062b833f |
| publicationDate |
2016-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016172219-A1 |
| titleOfInvention |
Methods and compositions for inhibition of toll-like receptors (tlrs)-mediated inflammation |
| abstract |
The invention is directed to a compound that binds to a Toll-like Receptor (TLR) and prevents TLR-mediated inflammation. The present invention is further directed to methods for blocking an interaction between TLR and MyD88 and/or TRIF, methods for inhibiting TLR-mediated inflammation in a mammalian cell, methods for preventing and/or treating a mammal suffering or at risk for suffering from TLR-mediated inflammation, and methods for preventing and/or treating a mammal suffering or at risk for suffering from a disorder related to TLR-mediated inflammation (e.g., chronic inflammatory disorders). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3737703-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020243787-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108084269-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3980440-A4 |
| priorityDate |
2015-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |