| abstract |
This present invention relates to genetic mutations that may be used to evaluate the risk of Lewy body disease in a subject. This invention is based, at least in part, on the discovery that genetic mutations in the genes GBA, SMPD1, HEXA and MCOLN1 are associated with Lewy body disease. As such, these mutations may be used in methods of diagnosing and treating Lewy body disease patients. |