| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08387c7f1a7b697d85d1e2c576596516 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1866 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 |
| filingDate |
2015-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e56d828fedeae374e039f0d59d6c4c91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7918a2bfa376f44bfd78195104f61fbc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ac755e8d4b7f590d22fb9df81a09ef8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_891582548b05de792ed30352ebaa9fb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84f539b05042b276c13c1efd66ad7a75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a8b749f4d13aa9db521d913fc6660de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_029add65fd0cfb6f8925a7c31af83b25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_866fdf95ffb1dbd789f88b0f6e89d84a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d31f650eae547ec991d18dec75894c0c |
| publicationDate |
2016-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016163912-A1 |
| titleOfInvention |
Codon-optimized recombinant plasmid, method of stimulating peripheral nerve regeneration, and method of treating nerve damage in humans |
| abstract |
The invention relates to medicine, and more particularly to neurosurgery and trauma surgery, and can be used for stimulating nerve regeneration through the use of a gene therapeutic construct which codes for vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF-2). The gene therapeutic construct that codes for the two factors is based on a codon-optimized recombinant plasmid. The gene therapeutic construct can be introduced either directly into a damaged nerve or into the perineural tissues either during surgery or in the post-operative period. The invention significantly improves the outcomes of the reconstructive treatment of damaged peripheral nerves. |
| priorityDate |
2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |