| abstract |
The present invention relates to a radioactive probe for detecting in vivo hydrogen sulfide and, more specifically, to a probe for detecting hydrogen sulfide comprising a complex compound into which a radioactive isotope Cu is introduced. According to the embodiments of the present invention, as a result of observing, in real-time, animal models in which a large amount of hydrogen sulfide involved in various diseases is generated, through optical and nuclear medicine imaging, the probe for detecting hydrogen sulfide according to the present invention can selectively provide images of a site in which hydrogen sulfide has abnormally increased in a cell or a tissue, by selectively combining to hydrogen sulfide, whereby the probe can detect a disease in an unexpected site without affecting the anatomical properties of body parts. In addition, the probe for detecting hydrogen sulfide quickly reacts with hydrogen sulfide, whereby the probe can resolve the existing problem of required wait time for testing after an imaging agent is injected. As such, the probe can be effectively used as a disease detection means such as an imaging composition, an imaging method, etc. |