| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3747bf64d40e3a84d36f688cd74b5bc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-915
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2519bb00be8b8ed329fd70d83cb371bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd99e47687a7af705f97e0ca27543997 |
| publicationDate |
2016-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016162385-A1 |
| titleOfInvention |
Bacterial system for the identification of amyloidogenic peptides and the screening of inhibitors of amyloidosis |
| abstract |
The invention relates to a bacterial system useful for the in vivo identification of amyloidogenic peptides and inhibitors of amyloid protein aggregation, based on the expression of a fusion protein that comprises the amyloidogenic peptide under study bound to a bacterial translation termination factor. Therefore, the invention provides such a fusion protein, a bacterial cell that expresses it, a method for identifying amyloidogenic peptides and a method for identifying inhibitors of amyloid protein aggregation in which the bacterial cell is cultured and the phenotypic changes produced as a consequence of the alteration in protein translation caused by the aggregation of the translation termination factor in the fusion protein are visualised. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11279745-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020114996-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3663311-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466278-B2 |
| priorityDate |
2015-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |