| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_689d532e7f712c780cb4cec200f16fef |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-04019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-332
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 |
| filingDate |
2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e28a4ee157e75f69da187ac92c30a770
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd53f28499d3b03650c54b5894bfe0ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb50a7af7861ac98dee2faa21400e4d9 |
| publicationDate |
2016-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016154675-A1 |
| titleOfInvention |
Platform for non-natural amino acid incorporation into proteins |
| abstract |
A complement to tRNAs and a protein translation system are provided that enable the incorporation of non-natural moieties such as non-natural amino acids without compromising the ability to incorporate all of the twenty natural amino acids into the protein. This is achieved by reassigning one of the tRNA anticodons for amino acids that are normally decoded by at least two different tRNA anticodons to a non-natural moiety, wherein at least one codon can be uniquely recognized by the reassigned anticodon and at least one another codon from the same codon box cannot be recognized by the reassigned anticodon. Accordingly, an mRNA for translation is engineered to comprise one or more specific codons corresponding to the reassigned tRNA anticodons so that the non-natural moiety is incorporated into the translated protein at a selected position. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017151997-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11732002-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023044431-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20230028363-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11787836-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542299-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108410827-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108410827-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11685942-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022175863-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019193416-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11492369-B2 |
| priorityDate |
2015-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |