| abstract |
Disclosed is a vaccine comprising an antigen and CD40L, wherein the antigen may be encoded by a first nucleic acid and CD40L may be encoded by a second nucleic acid. Also disclosed are methods for increasing an immune response in a subject, the methods comprise administering the vaccine to the subject in need thereof. Further disclosed is the antigen selected from the group consisting of a human papilloma virus (HPV) antigen, a human immunodeficiency virus (HIV) antigen, an influenza antigen, and a Plasmodium falciparum antigen. |