Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-1871 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-1871 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-38 |
filingDate |
2016-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcd2b86049a600d5471b03f600539a54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f64c59ea2c2c18ccca126dfeadf84094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4455285d8f70394fe1481b265d3a9c72 |
publicationDate |
2016-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2016149088-A1 |
titleOfInvention |
Use of alkaline washes during chromatography to remove impurities |
abstract |
In certain embodiments, the invention provides a method of purifying a protein of interest from a mixture which comprises the protein of interest and one or more contaminants, said method comprising: a) subjecting the mixture to a first chromatography matrix, wherein the protein of interest binds to the first chromatography matrix; b) contacting the first chromatography matrix with a first wash solution which has a pH of at least 9.0, and does not comprise arginine or an arginine derivative; and c) eluting the protein of interest from the first chromatography matrix into an elution solution. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10925986-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021076489-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11369707-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021191684-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11717586-B2 |
priorityDate |
2015-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |