http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016141363-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2016-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5045b46740d41478a1187d44218633e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afc5ab89ae53f3905b9f5f146039386a |
| publicationDate | 2016-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016141363-A3 |
| titleOfInvention | Glucose/galactose biosensors and methods of using same |
| abstract | Provided herein are glucose and galactose biosensors and methods of making and using the same. The biosensor may include a) a polypeptide comprising a ligand binding site and (i) one or more mutations as compared to wild-type E. coli GGBP; and b) a reporter conjugated to the polypeptide, and wherein the ligand is selected from the group consisting of glucose, galactose, and a combination thereof. In some embodiments, the reporter is conjugated to F16C. In some embodiments, the polypeptide further comprises (ii) at least one additional mutation that replaces an amino acid with a cysteine. Further provided herein is a panel comprising a plurality of biosensors as described herein. Further provided herein is a method of determining the concentration of glucose, galactose, or a combination thereof, in a sample from a subject. |
| priorityDate | 2015-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.