http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016141040-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c289ce0583c6e51a88b911c3bc8a3afd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_049b1dc6fc7a076d39d0aa59d571ab02 |
| publicationDate | 2016-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016141040-A1 |
| titleOfInvention | Homogenous entropy-driven biomolecular assay (heba) |
| abstract | A method for detecting an analyte in a sample includes the steps of binding a first catalytic precursor to the analyte at a first epitope and binding a second catalytic precursor to the analyte at a second, different epitope to generate a catalytic complex. The catalytic complex is reacted with a multiplex molecular substrate to generate a first target molecule and an intermediate substrate containing the bound catalytic complex. The intermediate substrate is reacted with a dummy reactant to generate a second target molecule, wherein the reaction further generates a waste molecule containing the dummy reactant and a free catalytic complex. An optical signal that is generated by one or more dye(s) specific to the first target molecule and/or the second target molecule is detected to detect the presence of the analyte in the sample. The overall reaction has substantially net zero enthalpy and a positive entropy change. |
| priorityDate | 2015-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.