| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b39777d0c0e12d6d738cffb192ff357b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-626
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2016-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca214bdd05d26988c82e8554a0683c9c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc24fd1073c7f6c720d4e19da34c128c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4969745586761f58693be7ee1214726
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7de5508db47459c138afda155d7ed046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf48c0feffd7305be20dbc8f48b44e34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37f76ef13eb54070006444cdac06e41e |
| publicationDate |
2016-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016135239-A1 |
| titleOfInvention |
Fusion protein comprising three binding domains to her2 |
| abstract |
The present invention relates to HER2 binding molecules comprising three binding domains for the same epitope (trivalent), or comprising a bivalent HER2 binding combined with an effector function. The invention also relates to trispecific HER2 binding molecules comprising three binders, each for a different epitope in the HER2 extracellular domain. The invention further comprises treatment of various HER2 expressing tumours comprising heterogeneic tumours and tumours or parts of it that are resistant to treatment with only a single epitope targeted therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11787862-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020221198-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019160501-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11530275-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4043494-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466094-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10640572-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019535234-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11732054-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7055794-B2 |
| priorityDate |
2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |