Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d1c64916674986ae6826cb4eec69163 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-13013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-01036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
filingDate |
2016-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f3c45d3b70f94479f87651d20502ac1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41018052ed2be5726242c284bfc57880 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eb82d8dea5f9a6910fa90c4fc5f39f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_819c48e1baaa54d950ec4c1891605088 |
publicationDate |
2016-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2016130845-A1 |
titleOfInvention |
A method for utilizing engineered dendritic cells to induce gut-homing regulatory t cells and treat gut inflammation |
abstract |
Gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme. A method for treating one or more than one inflammation-related condition or disease, the method comprising administering gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10577669-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3806864-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110082538-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021016474-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110082538-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017214190-A1 |
priorityDate |
2015-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |