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publicationDate 2016-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2016130449-A1
titleOfInvention Dose synthesis card for use with automated biomarker production system
abstract Microfluidic radiopharmaceutical production system and process for synthesizing per run approximately, but not less than, ten (10) unit doses of radiopharmaceutical biomarker for use in positron emission tomography (PET). A radioisotope from an accelerator or other radioisotope generator is introduced into a reaction vessel, along with organic and aqueous reagents, and the mixture heated to synthesize a solution of a pre-selected radiopharmaceutical. The synthesis process reduces waste and allows for production of biomarker radiopharmaceuticals close to the location where the unit dose will be administered to the patient. On-site, as-needed production of radiopharmaceuticals in small doses reduces the time between synthesis of the radiopharmaceutical and administration of that radiopharmaceutical, minimizing loss of active isotopes through decay and allowing production of lesser amounts of radioisotopes overall.
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