abstract |
The present disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-17A (IL-17A), and provides an IL-17A binding polypeptide comprising the sequence EX 2 DX 4 AX 6 X 7 EIX 10 X 11 LPNL X 16 X 17 X 18 QX 20 X 21 AFIX 25 X 26 LX 28 X 29 - Also disclosed is the use of such an interleukin-17A binding polypeptide as a diagnostic, prognostic and/or therapeutic agent. |