http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016111834-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5ecf9e72fe65c93cddc1a30cef91028 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0013 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2015-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba68eb0898b89d5a5cc88299c0216aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6539cd59f82a6d6853b21bf6d6a6728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ff923c0658f7b14fdda6e49e7219767 |
| publicationDate | 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2016111834-A1 |
| titleOfInvention | Cox-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers |
| abstract | The present disclosure provides platinum-containing conjugates that selectively target and kill tumor/cancer cells. The conjugates contain a moiety that selectively targets COX-2, which is overexpressed by a broad range of tumor/cancer cells. The present disclosure provides conjugates that selectively target and kill tumor/cancer cells. The expression of cyclooxygenase II (COX-2) is upregulated in many benign and malignant tumor/cancer cells. In some embodiments, the conjugates comprise a COX-2-targeting moiety and a platinumcontaining antitumor agent. The term "antitumor agents" includes antitumor agents and anticancer agents. In some embodiments, the COX-2-targeting moiety comprises a non-steroidal anti-inflammatory drug (NSAID). In certain embodiments, the COX-2-targeting moiety comprises a COX-2-selective inhibitor. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9850183-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10053478-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017083595-A1 |
| priorityDate | 2015-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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