http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016108572-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
filingDate | 2015-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_136af05e516bda16e61842a57f53951e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_856b69741f9a50d8026b41f01ded46f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10c28fb64d9f1c36c0091bf3cc040f02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1c676bfecb23466060d2424cfb8c257 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feaa1e0dcaf17a4650077b3a65c529f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef105ed07c9b54709ca6e54903854ca5 |
publicationDate | 2016-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2016108572-A2 |
titleOfInvention | Composition for preventing and treating cholesterol-related diseases |
abstract | The present invention relates to a composition for preventing and treating cholesterol-related diseases and, more specifically, to a composition for preventing and treating cholesterol-related diseases, containing, as an active ingredient, a compound for inhibiting the linkage between PCSK9 and LDLR. The composition does not directly regulate the expression level of PCSK9 and/or LDLR in the liver, thereby lowering the resultant side effects; and effectively suppresses the linkage of PCSK9 and LDLR, thereby effectively lowering the total plasma cholesterol level and further increasing the therapeutic effect of a statin-based drug when administered in combination with the statin-based drug. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3664806-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11345705-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019032720-A1 |
priorityDate | 2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 253.